Ryan is an average college guy who has always been very unlucky with dating and relationships. What he thinks is a blow-off chemistry class instead leaves Ryan surprisingly inspired. Ryan decides to formulate an experiment to try to figure out the science behind dating. He gives himself two weeks to try and find out what he wants in a girl, as well as how to go about finding the perfect one for him. Ryan learns some things the hard way, but in the end, he knows one thing for sure: dating is all about chemistry.